Coronavirus disease-19 (COVID-19), which is brought on by the SARS-CoV-2, is a systemic illness that affects various organ systems, including the gastrointestinal tract. Acute Pancreatitis (AP) has been documented as a consequence or side effect of a variety of medications that have been administered to COVID-19 infected hospitalised patients. A variety of pathophysiological pathways lead to the development of Drug Induced Acute Pancreatitis (DIAP), and certain risk factors are crucial. A substance may be classified as having a definite, probable, or possible association with AP depending on the criteria used to diagnose DIAP. This review's objective is to list the drugs related with AP that are used to treat COVID-19. Corticosteroids, glucocorticoids, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), antiviral medications, antibiotics, monoclonal antibodies, estrogens, and anaesthetics are the key medications on this list. Additionally, DIAP must be prevented, especially in critically ill patients who may take many medications. The majority of DIAP management is non-invasive, and the initial step entails excluding the questionable medicine from the patient's therapy.
