Elif Calis, Asli Cakir, Mustafa Keskin and Ilknur Turkmen
Atypical Fibroxanthoma (AFX) is a rare cutaneous mesenchymal neoplasm, predominantly found on sun-damaged skin of the head and neck in elderly patients. But uncommonly it can develop on a burn scar with or without actinic damage. Malignancy development is the major complication of severe burns and the term Marjolin's ulcer has been accepted clinically. The most common malignancy in this setting are Squamous Cell Carcinoma (SCC), followed by Basal Cell Carcinoma (BCC) and Malignant Melanoma (MM). Mesenchymal tumours especially malign forms quite infrequently seen on scar tissue. Herein, we present a rare and unusual case of AFX arising on the non sun-damaged area within a chronic burn scar of a young patient. Four cases of burn-related AFX reported in the literature are reviewed and the histopathological features and differential diagnosis are discussed.