The administration of intravenous fluids is an essential component in the management of critically ill patients, especially those in septic shock, with the aim of increasing cardiac output and micro vascular perfusion. In order to optimize clinical decision making and therapeutic actions, a set of recommendations have been developed. In this sense, the guidelines Surviving Sepsis Campaign (SSC) have been the ones that have internationally guided the rapid administrationof at least 30 mL/Kg of crystalloids in this scenario. The current guidelines offer little room for adaptation in the recommendations for resuscitation with fluid therapy, proposing a homogenization in the confrontation quickly, neglecting the individualization of each patient, therefore the challengeis how to promote the guidelines or protocols and at the same time encourage personalized medicine.
