This article explores recent findings and developments related to the gut microbiome?s role in human metabolism. It summarizes key research, identifies metabolic pathways involved, and discusses emerging evidence from human and animal studies. The gut microbiome influences energy balance, glucose metabolism, lipid profiles, and inflammatory signaling, all of which have implications for metabolic health and disease prevention. The objective of this review is to provide an in-depth understanding of the physiological mechanisms by which the gut microbiota regulates host metabolism and to highlight potential clinical applications in personalized medicine and preventive health care.
