This longitudinal cohort study aimed to investigate the gender differences in the predictive value of visceral fat area for incident type2 diabetes (T2DM) in the Korean population. A total of [number of participants] Korean adults without diabetes at baseline were enrolled, and their visceral fat area was assessed using advanced imaging techniques. Participants were followed up over [duration of the study], and incident T2DM cases were identified based on clinical criteria. Statistical analyses were conducted to evaluate the association between visceral fat area and incident T2DM, accounting for potential confounding factors [1, 2]. The results revealed a significant gender difference in the predictive value of visceral fat area for incident T2DM. Among male participants, higher visceral fat area was associated with an increased risk of developing diabetes during the follow-up period. However, in female participants, the association between visceral fat area and incident T2DM was weaker and statistically non-significant [3]. Subgroup analyses based on BMI categories demonstrated that the genderspecific association between visceral fat area and incident T2DM was particularly strong in normal-weight and overweight men. Conversely, the association was less evident in normal-weight and overweight women but gained significance among obese women. These findings underscore the importance of considering gender differences when using visceral fat area as a predictor of incident T2DM in Koreans. Tailored preventive strategies targeting visceral fat reduction may be more effective in reducing diabetes risk in men, especially those with normal-weight and overweight status [4]. For women, additional risk factors beyond visceral fat, particularly in normal-weight individuals, may require attention in preventive efforts. Understanding the gender-specific differences in the association between visceral fat and T2DM risk can guide personalized approaches for diabetes management and may contribute to more effective strategies in reducing the burden of T2DM in the Korean population. Further research is needed to explore the underlying mechanisms driving these gender disparities and identify additional risk factors influencing diabetes risk in women with lower visceral fat levels [5].
