Valmore Bermudez, Juan Salazar, Robys Gonzalez, Angel Ortega, María Calvo, Luis Carlos Olivar, Jessenia Morillo, Edgar Miquilena, Mervin Chavez-Castillo, Rendy Chaparro, Mayela Cabrera and Joselyn Rojas
Objective: The purpose of this study was to evaluate the prevalence and risk factors associated with impaired fasting glucose (IFG) in adult individuals from Maracaibo city, Venezuela. Materials and methods: 2230 patients from the Maracaibo Metabolic Syndrome Prevalence Study were selected. IFG was defined according to the 2016 ADA criteria. A multiple logistic regression model was constructed in order to assess risk factors associated with IFG. Results: In the general population, the prevalence of IFG was 19.5% (n=435), with 46.4% (n=202) being women and 53.6% (n=233) being men, p=0.004. The main risk factors associated with IFG were age (≥60 years: OR=2.31; CI 95%=1.23-4.35; p<0.01), alcohol consumption, abdominal obesity and insulin resistance. After evaluating individuals with IFG exclusively, the major risk factor was the presence of elevated high-sensitivity C-Reactive Protein levels (OR=2.03; CI 95%=1.13-3.67; p<0.02). Conclusions: In Maracaibo the prevalence of IFG is similar to that of international reports. It is associated with a variety of risk factors, especially abdominal obesity, insulin resistance and low-grade inflammation, demonstrating the close link between adiposopathy and alterations in glucose metabolism.