Journal of Diabetes & Metabolism

ISSN - 2155-6156


Prevalence and Risk Factors associated with Impaired Fasting Glucose in Adults from Maracaibo City, Venezuela

Valmore Bermudez, Juan Salazar, Robys Gonzalez, Angel Ortega, María Calvo, Luis Carlos Olivar, Jessenia Morillo, Edgar Miquilena, Mervin Chavez-Castillo, Rendy Chaparro, Mayela Cabrera and Joselyn Rojas

Objective: The purpose of this study was to evaluate the prevalence and risk factors associated with impaired fasting glucose (IFG) in adult individuals from Maracaibo city, Venezuela. Materials and methods: 2230 patients from the Maracaibo Metabolic Syndrome Prevalence Study were selected. IFG was defined according to the 2016 ADA criteria. A multiple logistic regression model was constructed in order to assess risk factors associated with IFG. Results: In the general population, the prevalence of IFG was 19.5% (n=435), with 46.4% (n=202) being women and 53.6% (n=233) being men, p=0.004. The main risk factors associated with IFG were age (≥60 years: OR=2.31; CI 95%=1.23-4.35; p<0.01), alcohol consumption, abdominal obesity and insulin resistance. After evaluating individuals with IFG exclusively, the major risk factor was the presence of elevated high-sensitivity C-Reactive Protein levels (OR=2.03; CI 95%=1.13-3.67; p<0.02). Conclusions: In Maracaibo the prevalence of IFG is similar to that of international reports. It is associated with a variety of risk factors, especially abdominal obesity, insulin resistance and low-grade inflammation, demonstrating the close link between adiposopathy and alterations in glucose metabolism.