General Medicine: Open Access

ISSN - 2327-5146


Synchronous Orbital and Gastric Metastasis of Invasive Lobular Breast Carcinoma, Mimic Primary Gastric Carcinoma-Case Report

Young Jin Choi, Young Duck Shin, Young Jin Song, Ho Chang Lee and Seung-Myoung Son

Breast carcinoma is the most common primary origin of orbital metastasis. Orbital metastasis occurs through hematogenous spread and predominantly involves the choroid. On the other hand, breast carcinoma metastasis to the stomach is relatively rare. Invasive lobular carcinoma has a high tendency to metastasis to the stomach than ductal carcinoma. We present a case of invasive lobular carcinoma of breast with synchronous presentation of orbital and gastric metastasis. Gastroscopy revealed diffuse schirrous mass with pyloric obstruction and the biopsy was poorly differentiated carcinoma, mimic primary gastric malignancy. But on immunohistochemistry, both orbital and gastric mass showed hormonal receptor positivity that is agreement with primary breast lesion. Clinical suspicion, repeated endoscopic procedures, and intimate histologic analysis including immunohistochemistry is necessary for appropriate diagnosis, which might help to avoid unnecessary surgical procedure owing to incorrect diagnosis.