Dermatology Case Reports

ISSN - 2684-124X


Thalidomide, A Rational Agent for Treatment of Multicentric Reticulohistiocytosis

Daniel J Zinn, Olive Eckstein, Mary L Olsen, Carl E Allen and Kenneth L McClain*

A patient with Multifocal Reticulohistiocytosis (MRH) of skin and joints failed treatment with etanercept, methotrexate, hydroxychloroquine, prednisone, bisphosphonates and hydroxyzine. Long term treatment with thalidomide led to marked improvement in joint and cutaneous manifestations.