Marc Donath* and Maria Catalina
Hyperglycemia and increased morbidity are hallmarks of diabetes mellitus (DM), a metabolic condition that affects people all over the world. Increased oxidative stress (OS) response and increased inflammatory response are two of hyperglycemia's harmful effects. DM impairs the liver's capacity to regenerate and is particularly linked to a poor prognosis after an injury caused by ischaemia-reperfusion (I/R). This review aims to present recent publications addressing the effects of DM (hyperglycaemia) on OS and the inflammatory process, which play a crucial role in I/R injury and impaired hepatic regeneration after liver surgery, in light of the growing need for knowledge of the impact of DM on the liver following a surgical procedure.
