ipgocr

Gynecology & Obstetrics Case report

ISSN - 2471-8165

Case Report - (2019) Volume 5, Issue 2

Idiopathic Granulomatous Inflammation Presenting as a Malignant Tumor-like Mass in the Uterine Cervix: A Case Report

 

Author info »

Abstract

A granulomatous inflammation is a distinctive inflammatory response incited by various infective, autoimmune, toxic, allergic, and neoplastic conditions. It rarely involves the uterine cervix, and its appearance may mimic that of cervical cancer, complicating the diagnosis. Herein, we report a rare case of cervical granulomatous inflammation that led to the formation of a malignant tumor-like growth. An 88-year-old postmenopausal woman with abnormal vaginal bleeding presented with a visible mass in the uterine cervix. Radiological investigations revealed a suspiciously malignant lesion extending into the left parametrium and the lower vagina. However, histopathological examination of sequential biopsy samples from the lesion revealed only granulomatous inflammation, with no evidence of malignancy. We followed an expectant management, as the etiology remained unknown. At 6 months, the mass lesion was observed to have reduced in size. Our experience indicated that idiopathic cervical granulomatous inflammation can be simply monitored without any therapeutic intervention after the definitive exclusion of a malignancy using histopathological examination, even if its appearance is similar to that of cervical cancer.

References

  1. Williams GT, Williams WJ (1983) Granulomatous inflammation - A review. J Clin Pathol 36: 723-733.
  2. Shah KK, Pritt BS, Alexander MP (2017) Histopathologic review of granulomatous inflammation. J Clin Tuberc Other Mycobact Dis 7: 1-12.
  3. Almoujahed MO, Briski LE, Prysak M, Johnson LB, Khatib R (2002) Uterine granulomas: Clinical and pathologic features. Am J Clin Pathol 117: 771-775.
  4. James DG (2000) A clinicopathological classification of granulomatous disorders. Postgrad Med J 76: 457-465.
  5. Christie AJ, Krieger HA (1980) Indolent necrotizing granulomas of the uterine cerfix, possibly related to chlamydial infection. Am J Obstet Gynecol 136: 958-960.
  6. Evans CS, Goldman RL, Klein HZ, Kohout ND (1984) Necrobiotic granulomas of the uterine cervix. A probable postoperative reaction. Am J Surg Pathol 8: 841-844.
  7. Wilson GE, Haboubi NY, McWilliam LJ, Hirsch PJ (1990) Postoperative necrotising granulomata in the cervix and ovary. J Clin Pathol 43: 1037-1038.
  8. Winters U, Watson AJ, Dalal NR (2005) A case of diffuse granulomas of the cervix. J Obstet Gynaecol 25: 225.
  9. Kelly P, McCluggage WG (2006) Idiopathic uterine granulomas: report of a series with morphological similarities to idiopathic ovarian cortical granulomas. Int J Gynecol Pathol 25: 243-246.
  10. Quinn MA, Benedet JL, Odicino F, Maisonneuve P, Beller U, et al. (2006) Carcinoma of the cervix uteri. FIGO 26th Annual Report on the Results of Treatment in Gynecological Cancer. Int J Gynaecol Obstet 95 Suppl 1: S43-103.

Author Info

 

Copyright:This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.