ipaad

American Journal of Advanced Drug Delivery

ISSN - 2321-547X

Research Article - (2013) Volume 1, Issue 2

Synthesis of Substituted 7-Methyl-2,8-Dihydropyrazolo[1,5-α][1,3,5]-Triazine Derivatives for Anti-Inflammatory and Anti- Microbial Screening

 

Author info »

Abstract

A series of condensed pyrazolo and triazine derivatives have been synthesized to their physical property melting point, % yield, retention factor (Rf) have been evaluated. Structure is confirmed by UV, IR, NMR and Mass. All synthesized compounds are screened for two biological activities (Anti-inflammatory and Anti-microbial). Anti-inflammatory activity has been carried out by rat paw edema method while anti-microbial activity has been carried out by filter paper disc method. MIC (minimum inhibitory concentration) for antimicrobial screening has been carried out by tube dilution method.

Author Info

 

Copyright:This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.