jdm

Journal of Diabetes & Metabolism

ISSN - 2155-6156

Review Article - (2022) Volume 13, Issue 9

The Medicinal Effects Of Abelmoschus Esculentus Of Type 2 Diabetes

Neeta Rai1*, Swati Mutha1, Amrita Thakur1 and Nisha Thakre2
 
*Correspondence: Neeta Rai, Department of Pharmaceutics, Vishwakarma University, Pune Maharashtra, India, Email:

Author info »

Abstract

Abelmoschus esculentus L., is commonly known as lady's fingers, Bhindi, okra or gumbo, it is a flowering plant which belongs to family malvaceae. The geographical origin of okra is South Asian and West African origins. The plant is cultivated in the tropical, subtropical and warm temperature regions around the world. The species is an annual or perennial, growing up to 2 m tall. It is a health rich food due to its high fiber, vitamin C and folate content. It is rich in source of calcium and potassium. In addition, the plant also used medicinally in treatment of several disorders like Anti-cancer, Antimicrobial, Anti-ulcer activity, Antioxidant property The aim of present study is to highlight the reduction of blood sugar for the treatment of diabetes.

Keywords

Abelmoschus esculentus; okra; Antioxidant; folate; Anti-ulcer activity

Introduction

Abelmoschus esculentus L

Abelmoschus esculentus L. is commonly known as lady's fingers, Bhindi, okra or gumbo, is a flowering plant belongs to family malvaceae. The geographical origin of okra is South Asian and West African origins. The plant is generally cultivated in tropical, subtropical and warm temperature regions around the world. The species is an annual or perennial, growing up to 2 m tall. It is a popular and rich health food due to its contains high fiber, vitamin C and folate content. It is also known as flowering plant known for its edible seed pods [1].

It is an oligo- purpose crop, but they generally consumed for its green tender fruits as a vegetable in a different variety of ways. These fruits are rich in Vitamins, calcium, potassium and other mineral matters. The mature okra seed is a good source of oil and protein has been known to have superior nutritional quality. Okra seed oil is rich in unsaturated fatty acids such as linoleic acid, which is essential for human nutrition. Its mature fruit and stems contain crude fiber, which is used in the paper industry [2].

Description of Abelmoschus esculentus

Biological Name: Hibiscus esculentus, Abelmoschus esculentus

Synonyms: Kacang Bendi, Okra, okura, Okro.

Kingdom: Plantae

Order: Malvales

Genus: Abelmoschus

Species: A.Esculentus

Family: Malvaceae

Origin: Distributed from Africa to Asia, southern Europe and America.

Part used: Seeds, fruits, pea pods, root

Extract used: Water extract

Other Names: Kacang Bendi, qiu kui, Okra, okura, Okro, Quiabos, Ochro, Quiabo, Gumbo, Quimgombo, Bamieh, Bamya, Quingumbo, Bamia, Ladies Fingers, Bendi, Bhindi, Kopi Arab [2]. (Figures 1, 2)

diabetes-metabolism-Abelmoschus

Figure 1: Abelmoschus esculentus.

diabetes-metabolism-Esculentus

Figure 2: Abelmoschus Esculentus Flower.

Chemical constituents

Okra contains Flavonol glycoside, Phenolic compounds, 2.7% aqueous extract .Okra bast, a multicellular fiber was analyzed and the estimated average chemical compositions of OBF (Abelmoschus esculentus variety) are 67.5% a-cellulose, 15.4% hemicelluloses, 7.1% lignin, 3.4% pectic matter, 3.9% fatty and waxy matter and 2.7% aqueous extract [2, 3]. It is clear that the main constituents of OBF are a-cellulose, hemicelluloses and lignin and the rest are very minor in proportion, so render a little influence to the structure of OBF. Therefore, the structure of a-cellulose, hemicelluloses and lignin and the mode of combinations that exist in between themselves are dominating the structure of OBF [3]. (Table 1)

Energy 33 kcal
Carbohydrates 7.45 g (140
Sugars 1.48 g
Dietary Fibers 3.2 g
Fat 0.19g
Protein 2g
Water 90.19g
Vitamin A 36μg (7%)
Thiamine(B1) 0.2 mg (17%)
Riboflavin(B2) 0.06mg (5%)
Niacin (B3) 1mg (7%)
Vitamin C 23mg (28%)
Vitamin E 0.27 mg (2%)
Vitamin K 31.3 μg (30%)
Calcium 82mg (8%)
Iron 0.62 mg (5%)
Magnesium 57 mg (16%)
Potassium 299mg (6%)
Zinc 0.58 mg (6%)

Table 1: Okra Raw Nutrition Value per 100g.

Percentages are related to US recommendations to for adults. (Source: USFDA database) Okra is a popular health food due to its high fiber, Vitamin C, and folate content. Okra is also known for being high in antioxidants. Okra is also a good source of calcium and potassium.

Parts Used: fruit, leave seed and root [4].

Diabetes Mellitus

Diabetes happens when your body isn't able to take up sugar (glucose) into its cells and use it for energy .it describes a group of metabolic disease in which the person has high blood glucose (blood sugar). People living with type 2 DM are more vulnerable to various forms of both short- and long-term compligttgccations, which often lead to their premature death. This tendency of increased morbidity and mortality is seen in patients with type 2 DM because of the commonness of this type of DM, its insidious onset and late recognition, especially in resource-poor developing countries like Africa [4].

Diabetes mellitus is a chronic disorder of carbohydrates, fats and protein metabolism. A defective or deficient insulin secretary response, which translates into impaired carbohydrates (glucose) use, is a characteristic feature of diabetes mellitus, as is the resulting hyperglycemias. Diabetes mellitus (DM) is commonly referred to as a “sugar” and it is the most common endocrine disorder and usually occurs when there is deficiency or absence of insulin or rarely, impairment of insulin activity (insulin resistance) [5]. The International Diabetes Federation (IDF) estimates the total number of diabetic subjects to be around 40.9 million in India and this is further set to rise to 69.9 million by the year 2025 [6].

This results in a buildup of extra sugar in your bloodstream [7].

• Insulin production is inadequate.

• Body’s cell do not responded properly to insulin

• They are 4 types of diabetes [8].

• Type 1:- Type 1 diabetes is a chronic disease. In which cells in the pancreas make insulin are destroyed, for this reason body is unable to make insulin.

• Type 2:- The cells have stopped responding well to insulin. The body struggles to move glucose from the blood into the cells, despite having adequate levels of the hormone. Eventually, their bodies may stop making adequate insulin entirely.

• Pre diabetic: Prediabetes has a higher blood sugar level than normal blood sugar level. It's not high enough to be considered type 2 diabetes.

• Gestational: Gestational diabetes is diabetes diagnosed for the first time during pregnancy (gestation). Like other this is also types of diabetes, its affects how your cells use sugar. It causes high blood sugar that can affect your pregnancy and your baby's health.

How okra is help for diabetes?

Okra is a rich source of many nutrients, including fibre, vitamin B6, and folate. Vitamins B slow the progress of diabetic neuropathy and reduce levels of homocysteine, a risk factor for this disease [9]. The soluble fiber also helps stabilize sugar [10]. Okra is a vegetable that is widely consumed in India. It is cooked with a number of spices and eaten with chapatis. Who knew it could help us control symptoms of diabetes as well [11, 12].

How it is used?

Take 2 piece of lady finger & cut it both the end. Also put a small cut in the middle. After put the two piece of lady finger in glass of water & cover with glass and kept it room temperature during at night.

How it is consumed?

Early morning, before breakfast, remove these two pieces of ladies finger from the glass and simply drink this water. Keep doing it on a daily basis within two weeks .you will see remarkable results in the reduction of your sugar [13, 14].

Water extraction process for Okra [15, 16]

By Rotary Evaporator:

• 500 g seed powder was macerated

• Extracted with distilled water for 72 h at RT

• Chloroform was added to the mixture to prevent microbial contamination

• After completion of extraction, it was filtered

• Solvent was removed by evaporation in a rotary evaporator

• And the solid mass was freeze-dried

• The percentage yield obtained was 17% w/w (Figure 3) Health Benefits of Okra [17]

diabetes-metabolism-Reference

Figure 3: Reference image of rotary evaporator.

• Controls blood sugar: Okra contents high amount of soluble and insoluble fibers and having low glycemic index. For this so fiber helps us to maintain and stabilize the blood sugar by delaying the gastric emptying of sugar.

• Prevents Migraine: It contains mucus forming fiber, so they hold and keep you hydrating throughout a day

• Promote gut health: okra is rich in fiber which helps to move smoothly through the intestine.

• Promotes vision: okra is powerhouse of vitamin A and antioxidant like beta carotenes, xanthein and lutein are powerful compounds that destroy free radicals responsible for cell degradation and vision. So after taking regular intake of okra in your diet you can protect your eyes too.

Conclusion

The conclusion of this paper was studied that the water extract of Abelmoschus esculentus is used for the treatment of reducing the blood sugar level in humans. It is generally used to cure Type 2 Diabetes due to Non- Insulin depended condition.

REFERENCES

  1. Martin FW (1982) Okra, Potential Multiple- Purpose Crop for the Temperate Zones and Tropics. Econ Bot 36: 340-345.
  2. Google Scholar

  3. Kochlar SI (1986) Okra (lady finger) in tropical crops, a text book of economic botany 1: 263-264.
  4. Google Scholar

  5. Jain N, Jain R, Jain V, Jain S (2012) A review onAbelmoschus esculentus. Pharmacacia 1: 1-8
  6. Indexed at, Google Scholar

  7. Ahmed AM (2002)History of diabetes mellitus.Saudi Med J23: 373-378.
  8. Indexed at, Google Scholar, Crossref

  9. Kumar CR (1992) Basic Pathology, Prism PVT. Limited Bangalore, 5th edition, 1992: 569-587.
  10. Ross, Wilson (2010) Anatomy and Pathophysiology in Health and Illness, Churchill Livingstone Elsevier, 11thedition, 2010: 227-229.
  11. Diabetes mellitus history- from ancient to modern times. (accessed on 22nd July, 2011)
  12. Patlak M (2002)New weapons to combat an ancient disease: treating diabetes.FASEB J16:1853
  13. Indexed at, Google Scholar, Crossref

  14. Akash Prabhune (2017) Abelmoschus esculentus (Okra) potential natural compound for prevention and management of Diabetes and diabetic induced hyperglycemia: Review. Int J Herb Med 5: 65-68.
  15. Indexed at, Google Scholar

  16. Purva D, Sunita M (2017) A review on: Diabetes and okra (Abelmoschus esculentus). J Med Plants Res 5: 23-26
  17. Indexed at, Google Scholar

  18. Herbal Online Pharmacy World of Herbal Remedies and Alternative Medicine.
  19. Indexed at, Google Scholar

  20. Chopra RN, Nayar SL, Chopra IC (1986) Glossary of Indian Medicinal Plants (Including the Supplement). Council of Scientific and Industrial Research, New Delhi.
  21. Indexed at, Google Scholar

  22. Maramag RP (2013) Diuretic potential ofCapsicum frutescens,Corchorus olituriusL. andAbelmoschus esculentusL. Asian journal of natural and applied science 2: 60-69.
  23. Google Scholar

  24. Smit R, Neeraj K, Preeti K (2013) Traditional Medicinal Plants Used for the Treatment of Diabetes. Int J Pharm Phytopharmacological Res 3: 171-175.
  25. Indexed at, Google Scholar

  26. Vaidya MV, Nanoti MV (1989) Bhindi seed powder as coagulant in removal of turbidity from water. Indian J Environ 31: 43-48.
  27. Indexed at, Google Scholar

  28. Jarret RL, Wang ML, Levy IJ (2011) Seed oil and fatty acid content in okra (Abelmoschus esculentus) and related species. J Agric Food Chem 59: 4019-24.
  29. Indexed at, Google Scholar, Crossref

  30. https://www.netmeds.com/health-library/post/6-astonishing-health-benefits-of-okra.

Author Info

Neeta Rai1*, Swati Mutha1, Amrita Thakur1 and Nisha Thakre2
 
1Department of Pharmaceutics, Vishwakarma University, Pune Maharashtra, India
2Department of Pharmaceutics, Lakshmi Narain College of pharmacy, Bhopal; Madhya Pradesh, India
 

Citation: Neeta Rai, Swati Mutha, Amrita Thakur, Nisha Thakre. The Medicinal Effects of Abelmoschus Esculentus of Type 2 Diabetes. J Diabetes Metab, 2022, 13(9): 953.

Received: 02-Sep-2022, Manuscript No. jdm-22-19062; Editor assigned: 05-Sep-2022, Pre QC No. jdm-22-19062(PQ); Reviewed: 19-Sep-2022, QC No. jdm-22-19062; Revised: 23-Sep-2022, Manuscript No. jdm-22-19062(R); Published: 30-Sep-2022, DOI: 10.35248/2155-6156.1000953

Copyright: ©2022 Rai N, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Sources of funding : No Funding