Bullous pemphigoid is the most common autoimmune subepidermal blistering disease. Its onset is usually after 60 years of age. Characteristically, BP is an intensely pruritic eruption with widespread blister formation. However, in our case, patient characteristically developed lesions on 15th day post total knee replacement surgery and localized around surgical site. This indicates, physical trauma in form of surgical site incision as trigger. Localized BP is rare in itself and can be confused with irritant contact dermatitis, allergic contact dermatitis, and bullous cellulitis. Early recognition of this entity is important so as to determine prognosis and course of disease.
