Abiola T
Biochemistry Unit, College of Natural and Applied Sciences,
Ipetumodu, Ile-Ife, Osun State
Nigeria
Research Article
Assessment of the Antidiabetic Potential of the Ethanolic Extract of Date Palm (Phoenix Dactylifera) Seed in Alloxan-Induced Diabetic Rats
Author(s): Abiola T, Dibie DC, Akinwale OJ and Shomuyiwa OAAbiola T, Dibie DC, Akinwale OJ and Shomuyiwa OA
Background: Reports exist of the allopathic use of dates as a hypoglycemic, antioxidant and anti-diabetic agent. Date palm seed have also been found to be of nutritional and medicinal value.
Aim: this study was aimed at evaluating the anti-diabetic potential of the ethanolic extract of date palm seed in alloxan-induced diabetic rats.
Methodology: Proximate composition of date palm seed was determined using standard methods. Ethanolic extract of date palm seed was prepared by crude extraction protocol. The total flavonoids, phenolic contents and total antioxidant capacity of the seed extract was determined. Also, the scavenging activity of the extract using 1, 1- diphenyl-2-picrylhydrazyl (DPPH), nitric oxide (NO) and the reducing power was also evaluated. Thirty wistar rats were randomly divided into five groups of six r.. View More»
