André Fragoso
Portugal
Research Article
Magnesium and Mortality in Patients with Diabetes and Early Chronic Kidney Disease
Author(s): Ana Paula Silva, André Fragoso, Cláudia Silva, Nelson Tavares, Nélio Santos, Hercília Martins, Kristina Gundlach, Janine Büchel, Ana Camacho, Marília Faísca, Ilídio Jesus Varela and Pedro NevesAna Paula Silva, André Fragoso, Cláudia Silva, Nelson Tavares, Nélio Santos, Hercília Martins, Kristina Gundlach, Janine Büchel, Ana Camacho, Marília Faísca, Ilídio Jesus Varela and Pedro Neves
Objective: Cardiovascular disease is extensively described as being associated with chronic kidney disease, representing the most important cause of morbidity and mortality in these patients. Recent studies have suggested that hypomagnesaemia may be involved in the pathogenesis of cardiovascular disease in chronic kidney disease patients.
Methods: An observational, prospective study involving 191 diabetic patients at chronic kidney disease stages 1-3 divided into groups according to baseline levels of magnesium; 1: < 1.2 mg/dL, 2: 1.2-2.3 mg/dL and 3: ≥ 2.3 mg/dL. Different serum parameters were analyzed and compared between Mg levels. Carotid eco-Doppler and transthoracic echocardiography were also used to assess calcification features Statistical tests were used to find predictors of cardiovascular mortality, hospitalizations and dis.. View More»
