Colin M Kenny
Department of Medicine, Tripler Army Medical Center, 1 Jarrett White Rd, Honolulu, HI 96859
Tanzania
Case Report
Newborn Girl with Rapidly Progressive Linearly Distributed Vesicles and Pustules
Author(s): Colin M Kenny, Deptmer M Ashely and Sunghun ChoColin M Kenny, Deptmer M Ashely and Sunghun Cho
One-day old infant girl, born at term, presents with blanching erythematous macules, vesicles and pustules scattered on her upper and lower extremities. These lesions progressed rapidly and began to coalesce and take on a linear configuration, even appearing on her trunk and face. A punch biopsy revealed eosinophilic spongiosis. Based on skin findings and histopathology this girl was diagnosed with Incontinentia pigmenti (IP) in accordance with the IP Diagnostic Criteria 2013. IP is a rare, X linked dominant genetic syndrome occurring in 1 of 50,000 births. IP presents with characteristic cutaneous lesions and in varying frequency, extracutaneous manifestations. The cutaneous manifestations appear in four progressive stages. The first stage consists of multifocal and coalescing erythematous macules and patches with overlying tense vesicles on the patient’s trunk and extremities... View More»
