Erika B Rangel
Division of Nephrology, São Paulo Federal University,
Rua Botucatu, 740, Vila Clementino, SP 04023-900, Sao Paulo
Brazil
Research Article
Prevalence of Cardiovascular Risk Factors on Different Phases of Diabetic Nephropathy in Comparison to Type 1 Diabetes Recipients who had Undergone Simultaneous Pancreas Kidney Transplant
Author(s): Maria Deolinda F Neves, Erika B Rangel, João R Sá and Sergio A DibMaria Deolinda F Neves, Erika B Rangel, João R Sá and Sergio A Dib
The aims of this study were to evaluate the relationship between different phases of diabetic nephropathy and the beneficial effect of successful simultaneous pancreas-kidney transplant (SPKT) on the prevalence of cardiovascular risk factors (CVRF). We analyzed 210 type 1 diabetic patients (age>18 years and diabetes duration ≥ 10 years). Patients were divided into five groups: normo, micro, macroalbuminuric, end stage renal disease (ESRD), and SPKT. The following CVRF, besides diabetes, were analyzed: blood pressure, waist circumference, HDL cholesterol and triglycerides. The prevalence of ≥ 2 CVRF increased from normoalbuminuric to end stage renal disease group: 20.7%, 43.4%, 53.6%, 71.4% (p<0.001), respectively. In the SPKT group, this prevalence was 18.5%. Two or more CVRF were positive.. View More»
