Hubermont G
Belgium
Research Article
Does Peripheral Neuropathy Have a Clinical Impact on the Endovascular Approach as a Primary Treatment for Limb-Threatening Ischemic Foot Wounds in Diabetic Patients?
Author(s): Alexandrescu V and Hubermont GAlexandrescu V and Hubermont G
Approximately 15% of diabetic patients will develop a foot ulcer during their lifetime and among them, 14% to 43% will require amputation [1-3]. Peripheral neuropathy, such as chronic inferior limb ischemia, is a common complication of diabetes mellitus, affecting approximately 60% of diabetic patients and up to 80% of diabetic patients with foot ulcers [1-4]. Although the neuropathic etiology is dominant in 45% of diabetic foot ulcers, both ischemic and neuropathic risk factors are found in up to 35% of cases [1-4] Current clinical management, focused on the endovascular approach as a primary treatment for critical limb ischemia (CLI), is highly feasible and shows low complication rates [5,6] and limb salvage rates comparable to surgery [5-8]. Although diabetic neuropathy has already been reported as an important risk factor for limb loss independently from limb-threatening ischemia,.. View More»