Jerzy Starzyk
Poland
Case Report
Effectiveness of Metformin Treatment in the Teenager with Maturity-Onset Diabetes of the Young Type 3 and Oligomenorrhoea: A Case Presentation
Author(s): Anna Wędrychowicz, Marta Ciechanowska, Małgorzata Stelmach and Jerzy StarzykAnna Wędrychowicz, Marta Ciechanowska, Małgorzata Stelmach and Jerzy Starzyk
Sulphonyloureas are a treatment of choice for Maturity-Onset Diabetes of the Young type 3 (MODY3) young patients with excellent results, although they should be used with a great caution. In adult MODY3 patients hypersensitive response to sulphonyloureas and a decreased response to metformin in compare to sulphonyloureas were reported.
A case of teenager with MODY 3 and oligomenorhoea, successfully treated with metformin is presented.
A fifteen and a half year-old girl was diagnosed with oligomenorrhoea. Due to detected glucosuria and blood glucose (BG) at 267 mg/dl she was referred to a pediatric endocrinologist. She did not present with typical diabetes mellitus (DM) symptoms, however she had a three generations family history positive for insulin-dependent DM. She presented with a good clinical condition. The underweight (Body mass index 18.7 kg/m2) and discrete.. View More»
