Department of Genetics, Yale University School of Medicine, New Haven, Connecticut 06510, USA
Jijun Cheng Department of Genetics, Yale University School of Medicine, New Haven, Connecticut 06510, USA Non-coding genome; CRISPR-Cas9; sgRNA library; Molecular chipper; Reporter screen; Next generation sequencing The functions of the vast majority of non-coding sequences
CRISPR Cas9 technology and near base-resolution sgRNA library to identify non-coding functional regions.
miRNA and epigenetic regulation of hematopoietic stem cells and malignancy.
Discovery of novel TET2 targeting molecules for leukemia therapy.
microRNA biogenesis, targeting and regulatory mechanisms.
sgRNA library screen to identify novel non-coding regions regulating embryonic stem cell function.