Jose R Romero
Tanzania
Commentary
Serum Amylin Indicates Hypertriglyceridemia in Pre-diabetics
Author(s): Leonardo M Porchia, Enrique Torres-Rasgado, Elba Gonzalez-Mejia M, Ricardo Perez-Fuentes, Alicia Rivera, Martha Rodriguez-Moran, Fernando Guerrero-Romero and Jose R RomeroLeonardo M Porchia, Enrique Torres-Rasgado, Elba Gonzalez-Mejia M, Ricardo Perez-Fuentes, Alicia Rivera, Martha Rodriguez-Moran, Fernando Guerrero-Romero and Jose R Romero
Background: Hypertriglyceridemia is associated with increased insulin secretion and the incidence of Type 2 Diabetes. Studies in rodents and obese children have proposed a relationship between hypertriglyceridemia and elevated plasma amylin levels. However, there are limited data regarding serum amylin and triglyceride levels in adult human subjects with impaired glucose tolerance. In this study, we evaluated the association between serum triglycerides with circulating amylin levels in adult subjects with and without impaired glucose tolerance.
Methods: Glucose, insulin, Hemoglobin A1c, triglycerides, total amylin and unreduced amylin levels were determined in 80 non-pregnant females and 60 males enrolled in a cross-sectional study. Subjects were allocated according to their glucose tolerance status into normal glucose toler.. View More»
