Marlena Błazik
Poland
Research Article
Improving the Estimation of Meal-Time Insulin Dose Based On the Glycaemic Load of a Meal in Children with Type 1 Diabetes on Insulin Pump Therapy: A Randomized Study
Author(s): Lidia Groele, Dominik Golicki, Marlena Błazik and Ewa PańkowskaLidia Groele, Dominik Golicki, Marlena Błazik and Ewa Pańkowska
Background: The aim of the study was to assess whether an Insulin-Carbohydrate Ratio (ICR) increased by 30% per meal with a high glycaemic load allows postprandial glucose excursion to be maintained in control in children with type 1 diabetes.
Methods: A total of 70 children on insulin pump therapy participated in the study. They were stratified into age groups: 4-7 years of age, 8-12 years of age and above 12 years of age. The experimental Group (A) received an insulin dose based on individualised ICR increased by 30% for breakfast containing cornflakes with milk. The control group (B) received an insulin dose based on standard individualised ICR. The glycaemic load of the meal was adjusted to the age group (24,3; 32,4; 40,5). We assessed metabolic effects such as the area under the glucose curve (AUC), glucose increment, risk of hyperglyca.. View More»
