Masami Tanaka
School of Medicine,
35 Shinanomachi, Shinjukuku, Tokyo 160-8582
Japan
Research Article
Sex Difference in the Relationship among Sufficiency of Vitamin, Metabolic Bone Markers, and Aging
Author(s): Masami TanakaMasami Tanaka
Objective: If bone absorption exceeds bone formation, bone mineral density decreases. If concentration of parathyroid hormone (PTH) is high and concentration of estrogen is low, bone absorption is accelerated. Deficiency in vitamin D and K leads to deterioration of bone quality, which leads to increased risk of fracture. We evaluated the relationship among age, sufficiency situation of vitamins, bone metabolic markers, and PTH according to man and woman in order to identify high risk group of fracture.
Methods: The subjects are 207 workers in Keio University who took staff medical examination. As markers evaluating the sufficiency of vitamins, 25-hydroxy vitamin D (25(OH)D) and undercarboxylated osteocalcin (ucOC) were measured. Bone alkaline phosphatase (BAP), tartrate-resistant acid phosphatase (TRACP)-5b, intact PTH, calcium (Ca) and phos.. View More»