Journal of Diabetes & Metabolism

ISSN - 2155-6156


Mazen Alsahli

Mazen Alsahli
531 Davis Dr, Newmarket, ON L3Y 6P5,

  • Research Article
    Hypoglycemia with New –Generation Basal Analog Insulins: A Descriptive Critical Review
    Author(s): Mazen Alsahli, James R Thrasher and John E GerichMazen Alsahli, James R Thrasher and John E Gerich

    Optimizing the treatment of people with diabetes relies on balancing the benefits of glycemic control with the risk of hypoglycemia. Although insulin is essential for treating patients with type 1 diabetes mellitus (T1DM), patient and physician concerns regarding an increased risk of hypoglycemia can lead to delays in initiating insulin treatment in patients with type 2 diabetes mellitus (T2DM). This clinical inertia contributes to reduced glycemic control and poorer outcomes for patients. Advances in insulin agents have reduced the risk of hypoglycemia. In particular, the introduction of insulin glargine, the first basal analog insulin with a 24-hour glucose-lowering profile with no pronounced peak, represented a significant step towards achieving this goal. To further improve patient management, a number of insulin formulations and molecules are in development and are designed to h.. Read More»
    DOI: 10.4172/2155-6156.1000576

    Abstract PDF

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