Michela Gentile
Italy
Review Article
Searching For Prediabetes before Diabetes
Author(s): Gian Piero Carnevale Schianca, Mattia Bellan, Michela Gentile, Antonello Gibbin, Alessandro Gualerzi, Serena Favretto, Ettore Bartoli and Mario PirisiGian Piero Carnevale Schianca, Mattia Bellan, Michela Gentile, Antonello Gibbin, Alessandro Gualerzi, Serena Favretto, Ettore Bartoli and Mario Pirisi
Type 2 Diabetes Mellitus (T2DM) and pre diabetes prevalence is increasing worldwide at an alarming rate. Though many risk factors have been identified, the most appropriate strategy to identify when and who should undergo a more accurate screening, which could allow an earlier diagnosis and a more efficient prevention of complications, is still a matter of debate.
In this review we present data from a cohort of 2126 asymptomatic non diabetic subjects, who underwent an Oral Glucose Tolerance Test (OGTT). We have discussed our results sub-classifying our population according to the risk factors for diabetes development previously proposed by the American Diabetes Association.
According to our data, OGTT is able to identify a substantial proportion of subjects with prediabetic conditions who, if untreated, could progress to overt T2DM and potentially encounter serious health problems,.. View More»
