Mohammed A Hussein
Faculty of Pharmacy, October 6th University, 6th of October City,
Egypt
Research Article
Association of Cardiac Pro-B-Type Natriuretic Peptide Levels with Metabolic Risk Factors in Young Obese Egyptian Patients: A Focus on Normotensive vs. Hypertensive Patients
Author(s): Mona F Schaalan, Walid M Mohammad, Mohammed A Hussein and Naglaa A GobbaMona F Schaalan, Walid M Mohammad, Mohammed A Hussein and Naglaa A Gobba
Objective: In practice, there is increasing recognition of the importance of BNP in the pathophysiology, diagnosis and prognosis of ischemic cardiac dysfunction and heart failure. The association of BNP to obesity and characteristics of the metabolic syndrome in adults and aged patients is well established, but that in pediatrics needs thorough elucidation.
Methods: The aim of this study was to assess the association of plasma β-type natriuretic peptide (BNP) levels and metabolic risk factors in 40 young (average age was 13-17 years) obese normo- and hypertensive patients. This is achieved by assessment of serum levels of glucose, insulin, lipid profile as well as the proinflammatory cytokines, TNF- α, interleukin (IL)-6 and IL-23. The assessed metabolic indicators were compared with that of healthy .. View More»
