Nicolaou TE
Australia
Research Article
Relative Importance and Contribiton of Risk Factors for Diabetic Retinopathy and Macular Edema
Author(s): Xie J, Fenwick EK, Taouk Y, Nicolaou TE, Wang JJ, Wong TY and Lamoureux ELXie J, Fenwick EK, Taouk Y, Nicolaou TE, Wang JJ, Wong TY and Lamoureux EL
Purpose: This study determined the relative importance of risk factors for Diabetic Retinopathy (DR) and Diabetic Macular Edema (DME) and assessed their independent and joint contributions.
Methods: A prospective study of patients with type 2 diabetes was conducted in a tertiary eye hospital in Melbourne, Australia. Patients underwent a comprehensive eye examination and completed standardized administered questionnaires. Blood samples were assessed for glycated haemoglobin (HbA1c); fasting blood glucose; and serum lipids. Dilated fundus photographs were obtained and graded for DR and DME. The relative importance of the risk factors was determined by the independent and common variance explained in DR and DME using Commonality analysis.
Results: A total of 497 patients with type 2 diabetes were included in this analysis. The key risk factors accounted for 44.6% and .. View More»
