Rafael Pérez-Escamilla
Tanzania
Research Article
Low Plasma Hdl Cholesterol and Elevated C Reactive Protein further Increase Cardiovascular Disease Risk in Latinos with Type 2 Diabetes
Author(s): Mariana C Calle, Sonia Vega-López, Sofi a Segura-Pérez, Jeff S Volek, Rafael Pérez-Escamilla and Maria Luz FernandezMariana C Calle, Sonia Vega-López, Sofi a Segura-Pérez, Jeff S Volek, Rafael Pérez-Escamilla and Maria Luz Fernandez
The purpose of this study was to determine whether low plasma HDL and high C reactive protein (CRP) concentrations would further increase cardiovascular disease (CVD) risk in Latinos with poorly controlled type-2 diabetes, already at high risk for CVD. Subjects (n = 68) were grouped into High-HDL (? or 1.03 or 1.3 mmol/L) or Low-HDL (<1.03 or 1.3 mmol/L) for men and women, respectively. Following classification, risk factors for CVD including apolipoproteins, lipoprotein size and subfraction distribution were assessed. Similarly, participants were divided according to their CRP levels (? or <3 mg/L) and key inflammatory markers as well as leptin and adiponectin were analyzed. The Low-HDL group had higher concentrations of the atherogenic particles, large and medium VLDL and the smaller LDL subfractions compared to the High-HDL group (p<0.001). Consistently, VLDL diameter was .. View More»
