Ruchi Mathur
Tanzania
Research Article
Ethnic Diversity in Beta-Cell Function Susceptibility to Pancreatic Triglyceride Levels: Pilot Investigation
Author(s): Ildiko Lingvay, Ruchi Mathur, Edward W Szczepaniak and Lidia S SzczepaniakIldiko Lingvay, Ruchi Mathur, Edward W Szczepaniak and Lidia S Szczepaniak
Aims: Type 2 diabetes is a progressive disease and highly prevalent in Hispanic and Black minorities in the United States. Our research suggested that Black, compared to Hispanic and non-Hispanic White accumulate less of triglyceride within pancreatic tissue. Herein we describe ethnicity specific aspects of the relationship between pancreatic TG levels and beta cell function.
Methods: We studied 68 women: 16 Black, 26 Hispanic and 26 non-Hispanic White. We assessed insulin secretion and insulin sensitivity using frequently sampled glucose tolerance test - FSIVGTT, abdominal fat distribution using magnetic resonance imaging - MRI, and pancreatic triglyceride levels using proton magnetic resonance spectroscopy - 1H MRS.
Results: Characteristics and results were similar for non-Hispan.. View More»
