Vessela Koleva
Bulgaria
Research Article
Comorbidity of Obesity and Thyroid Dysfunction: An Association with Greater Cardiovascular Risk Factors
Author(s): Lachezar B Lozanov, Vessela Koleva, Bojan S Lozanov and Mira VankovaLachezar B Lozanov, Vessela Koleva, Bojan S Lozanov and Mira Vankova
Introduction: Hypothyroidism, metabolic syndrome and central obesity are common diseases known as the risk factors for atherosclerotic cardiovascular disease. The co-existence of thyroid dysfunction in obese patients might substantially increase the cardiovascular risk. The objective of the study was to evaluate the effect of hypothyroidism on the main cardiovascular risk factors in patients with obesity and cardiovascular syndrome.
Material and methods: In a cross-sectional clinical study we examined 202 patients with central obesity and metabolic syndrome (160 women, 42 men, aging 43 ± 13 yrs) with BMI ≥ 30 kg/m2 divided in two groups - 101 patients with subclinical or overt hypothyroidism (gr. A-hypot) and 101 eythyroid patients (gr B-eut), diagnosed by TSH, FT4,TPO-Ab. Laboratory assessment included: total cholesterol (TChol), .. View More»
