Department of Medicine, Austin Health, University of Melbourne, Victoria, Australia
Research Article
Diabetes and androgen-deprivation therapy-related diabetes in prostate carcinogenesis
Author(s): Jeffrey Zajac*
Regarding diabetes-related carcinogenesis and androgen deprivation
therapy-related metabolic disease, respectively, prostate cancer and ADT
are linked to diabetes. This study's objective is to thoroughly review the
pertinent literature. In the US, it is projected that 218,000 men receive a
new prostate cancer diagnosis each year. 10% of them are still discovered
to have metastases, while 30% of patients with nonmetastatic prostate
cancer had recently undergone ADT in addition to them. Contrary to
other cancers, type 2 diabetes has been linked to a decreased incidence
of prostate cancer, according to population-based studies. However,
more recent large cohort studies have found a link between diabetes and
advanced, high-grade prostate cancer. The greater likelihood of advanced
illness at diagnosis can be attributed to the lower serum testosterone and
.. View More»
DOI:
10.35248/2155-6156.1000963
