Changzhou People's Hospital, Xinhua District, China
Opinion
Ergosterol Enhances Renal Fiery Reactions in Mice Model of Diabetic Nephropathy
Author(s): Qian Gao*
Diabetic nephropathy (DN) is a prevalent and debilitating complication of diabetes mellitus, characterized by progressive renal dysfunction and inflammation. In recent years, there has been growing interest in exploring the impact of ergosterol, a sterol found in fungi, on various physiological processes. However, its influence on diabetic nephropathy remains poorly understood. This study aimed to investigate the effects of ergosterol on renal inflammatory reactions in a mouse model of diabetic nephropathy. Male C57BL/6 mice were induced to develop diabetes through streptozotocin administration and subsequently divided into two groups: one receiving ergosterol supplementation and the other serving as a control. Renal function, histopathological changes, and inflammatory markers were assessed after six weeks of treatment. Our findings reveal that ergosterol supplementation exacerbates .. View More»
DOI:
10.35248/2155-6156.10001067
