Journal of Next Generation Sequencing & Applications

ISSN - 2469-9853

+44 1250400002

Rahul M. Kohli

Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA


  • Commentary   
    DNA Sequencing Which is based on Nucleobase-Specific Partial Chemical Modification
    Author(s): Rahul M. Kohli*

    Maxim–Gilbert sequencing changed into the first widelyadopted method for DNA sequencing, and, at the side of theSanger dideoxy approach, represents the primary generation ofDNA sequencing methods. Maxim–Gilbert sequencing is nownot in giant use, having been supplanted with the aid ofsubsequent-technology sequencing methodsMaxam Gilbert sequencing is described as a technique of DNA sequencing that'sbased on nuclease- specific partial chemical amendment of DNAand next of DNA cleavage. Nuclease is defined as compoundscontaining nitrogen agencies .. View More»

    Abstract PDF