Sreenivasa C. Ramaiahgari, Ph.D
Biomolecular Screening Branch, National Toxicology Program, National Institute of Environmental Health Sciences
Sreenivasa C. Ramaiahgari is a Research Fellow in the Molecular Toxicology and Genomics Group within the Biomolecular Screening Branch of National Toxicology Program (NTP) of National Institutes of Environmental Health Sciences (NIEHS) located in Durham, North Carolina, USA.
In his current role Ramaiahgari is involved in development and validation of metabolically competent and physiologically relevant in vitro models for high-throughput toxicology studies. Ramaiahgari has extensive experience working with various three-dimensional cell culture models of liver, kidney, breast and prostate cancer cell types. Ramaiahgari will use these advanced in vitro models and apply novel methodologies including high content imaging and data-rich toxicogenomic approaches, e.g. Tox21 human sentinel 1500+ gene expression to study dynamic cellular stress responses upon environmental chemical exposure and extrapolate their effects on human health and disease. Ramaiahgari also contributes to several NTP in vitro screening assays.
Ramaiahgari obtained his B.S. in Biotechnology from Bangalore University, Bangalore, India followed by M.S. in Biotechnology from University of Abertay Dundee, Scotland, UK and a Ph.D. in Toxicology from Leiden University, Netherlands
Research interest includes Xenobiotic metabolism, Environmental toxicology, Liver and kidney toxicology, Gene expression analysis, High-throughput screening, high-content imaging, Next Generation Sequencing, in vitro biology, 3D organotypic models