Journal of Diabetes & Metabolism

ISSN - 2155-6156


Antidiabetic activity of Vinca rosea extracts in Alloxan induced diabetic rats

3rd World Congress on Diabetes & Metabolism

September 24-26, 2012 Marriott Convention Center, Hyderabad, India

Mohammed Fazil Ahmed, A. Srinivasa Rao, Mohd Abdul Irfan, Mohammed Azam and Mohammed Ibrahim

Scientific Tracks Abstracts: J Diabetes Metab

Abstract :

The present study was carried out to evaluate the antidiabetic activity of Vinca rosea methanolic whole plant extracts in alloxan induced diabetic rats for 14 days. The methanolic whole plant extract at high dose (500mg/kg) exhibited significant anti-hyperglycemic activity than whole plant extract at low dose (300mg/kg) in diabetic rats. The methanolic extracts also showed improvement in parameters like body weight and lipid profile as well as regeneration of β-cells of pancreas in diabetic rats. Histopathological studies reinforce the healing of pancreas, by methanolic Vinca rosea extracts, as a possible mechanism of their antidiabetic activity

Biography :

Mohammed Fazil Ahmed has completed his M.Pharmacy (Pharmacology) at the age of 25 years from Annamalai University and pursuing Ph.D in Pharmacology from Jawaharlal Nehru Technological University Hyderabad. He is the Associate Professor, of Nizam Institute of Pharmacy, Hyderabad. He has published more than 15 papers in reputed journals and serving as a reviewer for many International and National Journals.