Chrysoula Palazi
National and Kapodistrian University of Athens, Greece
Scientific Tracks Abstracts: Surgery Current Research
BACKGROUND The purpose of this study was the evaluation of the pressure-volume (PV) curve as it appears on the anaesthesia monitor, the recording and evaluation of parameters such as PO2 (partial pressure of oxygen), SaO2 (oxygen saturation of arterial blood), SpO2 (oxygen saturation) before intubation and intraope ratively, as well as the evaluation and recording of all possible complications in the pressure-volume curve (PPEAK - peak inspiratory airway pressure, PPLATE AU â?? plateau pressure) between the three groups of patients. METHODS The study took place in the Surgery Department of α recognized and highly qualified Cancer Memorial Hospital. Ninety patients diagnosed with abdominal cancer were included in the study and were divided in three groups. Group A consisted of oncological pa t ients with a normal history of pulmonary function and body mass index (BMI) values. Group B included oncological patients with a history of obstructive lung disease and Group C comprised oncological pa t ients with a history of restrictive lung disease. RESULTS PPEAK and PPLATEAU measurements at baseline were significantly higher for Group C than for the other two groups. PO2 for Group A was consistently higher throughout compared to those for Group B and Group C patients. PEEP usage differed only at the start of surgery between Group A and Group B, with Group B having a significantly higher value (p=0.009). FiO2 (fraction of inspired oxygen) was sig nificantly higher throughout for patients in Group C compared to patients in the other two groups. Re garding respiratory complications, it was found that rates of cough and shortness of breath differed signi f icantly between groups. The pressure-volume curve for Group A was characterized by a sigmoid form, for Group B patients, there was a concavity in the curve primarily in the final part, even when the initial part was not affected, and for group C patients there was a steep slope of the flow-volume curve and decrea sed FVC (forced vital capacity). CONCLUSIONS Monitoring lung function during general anaesthesia may provide useful information to the anesthetist and allow the quantification of the severity of respi ratory disease. The creation of pressure-volume (PV) curves provides important information about lung mechanics and ventilator setup. The evaluation of this PV curve with all its data (PPEAK, PPLATEU. FiO2 etc.) provides an ideal tool during anaesthesia and postoperatively, that may be useful for the safety of lung function under general anaesthesia.
Dr. Chrysoula Palazi, RN, MSc, PhD, is a distinguished nursing professional specializing in advanced clinical practice and healthcare leadership. She serves in the Department of Nursing at the School of Health Sciences, National and Kapodistrian University of Athens, Greece. With extensive academic and clinical expertise, she contributes to both education and research in the nursing field. Dr. Palazi is the Head Nurse of the Anaesthesiology Department at Metaxa Cancer Memorial Hospital in Greece. Her work reflects a strong commitment to excellence in patient care, oncology services, and perioperative nursing management.