Journal of Diabetes & Metabolism

ISSN - 2155-6156


Regulation of glucose homeostasis by adaptor proteins Nck

4th World Congress on Diabetes & Metabolism

August 14-16, 2013 Holiday Inn Chicago-North Shore, IL, USA

Louise Larose

Scientific Tracks Abstracts: J Diabetes Metab

Abstract :

Nck adaptor proteins, Nck1 and Nck2, exclusively composed of Src homology (SH) domains are well known to mediateintracellular signal transduction from activated plasma membrane receptor tyrosine kinases. Besides this, our group has recently reported a novel role forNck in mediating endoplasmic reticulum (ER) stress signaling through the unfolded protein response (UPR).

Biography :

Louise Larose has obtained her Ph.D. in Pharmacology from the University of Montreal in 1992 and completed her postdoctoral training at the Samuel Lunenfeld Research Institute in Toronto in 1995. As an Associate Professor from McGill University in Montreal, she has received the prestigious Chercheur National award from the FRSQ. Her work on the role of the adaptor proteins Nck in molecular mechanisms regulating plasma membrane receptor tyrosine kinases signaling and more recently the unfolded protein response has been published in reputed journals. She is serving as editorial board member, as well as ad hoc reviewer for important journals and panel members of several Canadian funding agencies.