Jamal Ahmad, Saba Noor and Iqbal Parwez
Aligarh Muslim University, India
Posters & Accepted Abstracts: J Diabetes Metab
A prospective study was carried on diabetic foot patients to deduce clinical attributes, the gamut of aerobic microbial flora and to appraise their comparative in vitro susceptibility to the customarily used antimicrobials. A detailed clinical chronicle and physical examination was carried out in each patient. The study also pivoted on assessing potential risk factors involved in development of non-healing ulcers. A total of 87 organisms were isolated from 70 specimens, and an average of 1.2 isolates per case was reported. Polymicrobial infection was found in 17% of subjects. In this study, Escherichia coli among the gram-negative (19.5%) and Staphylococcus aureus among the gram-positive (18.3%) were the predominant aerobes explored. Pseudomonas aeruginosa and Escherichia coli were pre-dominant isolates of non-healing ulcers. Amikacin exhibited highest sensitivity to gram-positive cocci (90.7%) and Enterobacteriace (86%). All strains of Pseudomonas aeruginosa were sensitive towards Imipenem (100%). Deplorable glycemic status, altered lipid spectra, existence of neuropathy and peripheral vascular disease possessed the potentiality for development of non-healing lesions. There is a need for continuous surveillance of bacteria and their antimicrobial sensitivity blueprints to provide the basis for empirical therapy and minimize the risk of complications. Also ardent clinical evaluation and history will aid in revealing the risk of developing non-healing status in DFUs.
Email: jamalahmad11@rediffmail.com
