Journal of Diabetes & Metabolism

ISSN - 2155-6156

Balachandar Nedumaran

Balachandar Nedumaran
Postdoctoral Fellow University of Colorado Denver United States


Postdoctoral Fellow (2015 – present) School of Medicine, University of Colorado Denver – Anschutz Medical Campus, CO, USA Visiting fellow (2011 – 2015) Cell Biology Group, Immunity, Inflammation and Disease Lab, NIEHS/NIH, RTP, NC, USA Postdoctoral fellow (2010 – 2011) Dept. of Dermatology, University of California, San Diego, CA, USA Researcher (2003 – 2004) Hormone Research Center, Chonnam National University, South Korea

Research Interest

Have strong experience on working with signal transduction pathways during my Ph.D.
Specifically, worked on the regulation gene expression by Nuclear Receptors and Transcription
factors. Found that Orphan nuclear receptor DAX-1 can control the gluconeogensis and lipogenesis
mediated by the Orphan Nuclear Receptor HNF4a and LXRa, respectively. Got very nice in vivo
training (mice experiments) during my Postdoctoral period. Working on different projects related
to the role of transcription factors in polycystic kidney disease and metabolism. Generated a new
X-gene-Knockout mice to investigate its role in various physiological functions. Performed
Tandem affinity purification (TAP) followed by Mass-spec analysis and identified some novel
interacting proteins with our protein interest. Conclusively, I have the lot of experiences in
exploring the regulation gene expression by nuclear receptors/transcription factors in various
physiological functions and metabolic disorders.