Natural Products Chemistry & Research

ISSN - 2329-6836


Luteolin-7-O-Glycosides from the Leaves of Centropogon cornutus (Campanulaceae)

Powder-George YL

A new luteolin-7-O-glycoside, named Centropogin A (1), together with three known luteolin-7-O-glycosides, Luteolin- 7-O-xyloside (2), Luteolin-7-O-[β-apiofuranosyl-(1→2)]β-xylopyranoside (3) and Luteolin-7-O-[β-glucopyranosyl- (1→2)-α-rhamnosyl-(1→6)] β-glucopyranoside (4) were isolated and purified via repeated chromatography of the n-BuOH soluble fraction from the methanol extract of the leaves of Centropogon cornutus (Campanulacae). The structures of these compounds were elucidated by analysis of their 1D-NMR (1H, 13C) and 2D-NMR (COSY, HSQC, HMBC), MS (HR-ESIMS) spectral data, and by comparisons with the literature data. This is the first report of secondary metabolites from the genus Centropogon and the first report of compounds (2)-(4) from the Campanulaceae family.