Natural Products Chemistry & Research

ISSN - 2329-6836


Synthesis, Reactions and Medicinal Importance of Cyclic Sulfone Derivatives: A Review

Md. Ashraful Alam, Kazuaki Shimada, Aklima Jahan, Md. Wahab Khan, Md. Mosharef H Bhuiyan, Mohammad Sayed Alam and Mohammed Mahbubul Matin

Sulfones or the cyclic sulfones are the type of organosulfur compounds that attract the special interest to organic chemists. Vast applications are observed in different fields with these types of sulfone containing compounds and their derivatives like in medicinal chemistry and also give the importance to many kinds of biological activity. The sulfones and their derivatives are used in many other fields as pharmaceutical and polymeric agents. Sulfone containing compounds are also used for the treatment of different diseases like dermatitis herpetiformis, leprosy, tuberculosis and others. The researchers have been giving much concentration to synthesize many types of sulfone compounds because of their various strong medicinal activities like as biological, antimalarial, antimicrobial, antiinflammatory, anticancer, anti-HIV, and anti-inflammatory and in other sectors also. These kinds of vast importance encourage us to study about the synthesis, reactions and applications of cyclic sulfones and their derivatives. The present article will provide some important information about the synthesis, reactions and applications of cyclic sulfone type compounds to the chemists to facilitate them in advance research works with more concentration which will be more beneficial for the society as well as for upcoming science generation.