Marcos Jose Salvador
Brazil
Research Article
Antioxidant and Cytotoxic Activities and Chemical Profile of Five Amaranthaceae Plants Collected in the South of Brazil
Author(s): Wallace Ribeiro Correa, Alvaro Jose Hernandez Tasco, Jane VN Marinho, Aislan CRF Pascoal, Joao Ernesto de Carvalho, Maria Salete Marchioretto and Marcos Jose SalvadorWallace Ribeiro Correa, Alvaro Jose Hernandez Tasco, Jane VN Marinho, Aislan CRF Pascoal, Joao Ernesto de Carvalho, Maria Salete Marchioretto and Marcos Jose Salvador
In this study, the antioxidant and cytotoxic activity, the phenolic content and the HPLC-DAD/ESI-MS profile of the ethanolic extracts of five Amaranthaceae plants collected in the south of Brazil were investigated: these were Alternanthera philoxeroides (Mart.) Griseb. (I), Alternanthera hirtula (Mart.) R.E. Fr. (II), Alternanthera praelonga A. St. –Hil. (III), Froelichia tomentosa (C. Mart.) Moq. (IV) and Pfaffia tuberosa (Spreng.) Hicken (V). The antioxidant potential was determined using the DPPH and ORAC-FL assays. The total phenolic content was measured using the Folin- Ciocalteu reagent. The ethanolic extracts of I, II, IV and V showed high levels of phenolic compounds (3.6-20.0 mg GAE/Kg), as well as high antioxidant activity in both methods. The cytotoxicity of the extracts was investigated in vitro against panel of human cancer cell lines and against VERO control. The e.. View More»
