Nesa L
Bangladesh
Research Article
Analgesic, Anti-Inflammatory and CNS Depressant Activities of Methanolic Extract of Sonneratia alba Leaves in Mice
Author(s): Asad S, Nesa L, Deepa KN, Sohel MdD and Kawsar MdHAsad S, Nesa L, Deepa KN, Sohel MdD and Kawsar MdH
Objectives: The present examine was going to evaluate the pain killer, anti-inflammatory, and CNS depressant activities of the methanolic extract of the Sonneratia clear leaves (MESAL). Materials and methods: By using carrageenan-induced inflamed method anti-inflammatory effects regarding MESAL were studied right here at the dose of 150 mg/kg and 300 mg/kg body mass. Analgesic activity of MESAL was evaluated by applying formalin-induced licking and gnawing at activities in mice at a dose of 200 mg/kg and 400 mg/kg body weight. The CNS depressant activity has been measured by observing typically the reduction of locomotors in addition to exploratory activities on view discipline and hole cross assessments at a dose regarding 200 and 400 mg/kg bodyweight. Results: Statistical analysis revealed that dose of 400 mg/kg displayed pct of protection (86.29%) of licking in addition to biting o.. View More»
