Natural Products Chemistry & Research

ISSN - 2329-6836

Padmanabhan R

Padmanabhan R


  • Research Article
    Phytochemical Investigation and In Vitro Antibacterial Evaluation on Root Extracts of Rumex abyssinicus
    Author(s): Melkamu Fufa F, Padmanabhan R and Gurmessa GTMelkamu Fufa F, Padmanabhan R and Gurmessa GT

    The dried and powdered root of Rumex abyssinicus was extracted with increasing gradient of solvents (petroleum ether, chloroform, acetone and methanol) and screened for antibacterial activity on four pathogenic bacterial strains: Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Salmonella thyphimurium. The acetone extract showed promissing antibacterial activity. Chromatographic separation of the acetone extract led to isolation of three compounds of which two of them (Betulone and oleic acid) were isolated for the first time from the plant. The structures of these compounds were charachterized with the help of spectroscopic methods (IR, NMR). Two compounds, RA-1 and RA-2, were identified to be betulone and oleic acid respectively based on spectroscopy data and literature reports, whereas the third compound RA-3 was only partially c.. View More»

    DOI: 10.4172/2329-6836.1000239

    Abstract PDF

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