Rajesh NG
Pune (MS)
India
Research Article
Anti-mycobacterial Activity of Selected Indian Botanicals Using Surrogate Mycobacterium Strains
Author(s): Rajesh NG and Archana DJRajesh NG and Archana DJ
The aim of the present study was to validate the traditional claims of selected botanicals such as as Amorphophyllus sylvaticus, Andrographis paniculata, Corallocarpus epigaeus, Dioscorea bulbifera (L), Dioscorea oppositifolia (L), Dioscorea pentaphylla (L), Dioscorea hispida (Dennst), Enicostema axillare (Lam Raynal), Gloriosa superba (L) and Morinda citrifolia (L) as possible inhibitors of Mycobacterial strains. Different solvent extracts along with flavonoid and alkaloid fractions of the selected ten medicinal plants were evaluated for their antimycobacterial activity against Mycobacterium smegmatis (NCIM 5138) and Mycobacterium phlei (NCIM 2240). The minimum inhibitory concentrations (MICs) were calculated for determining the efficacy of the selected botanicals. As a measure of quality control, High Performance Thin Layer Chromatography (HPTLC) fingerprint of flavonoids and alkalo.. View More»