Natural Products Chemistry & Research

ISSN - 2329-6836

Antipyretic effect of Erythrina lithosperma Miq., leaves infusion on rats (Rattus norvegicus)

5th International Conference and Exhibition on Pharmacognosy, Phytochemistry & Natural Products

July 24-25, 2017 Melbourne, Australia

Elisabeth N Barung, Juliet Tangka, Yos Banne, Jovie M Dumanauw and Destine Daity Lumepaa

Health Polytechnic Manado, Indonesia

Scientific Tracks Abstracts: Nat Prod Chem Res

Abstract :

Erythrina lithosperma Miq., leaves have been used as a traditional medicine to reduce fever. This study was aimed to examine the antipyretic effect of Erythrina lithosperma Miq., leaves infusion on rats (Rattus norvegicus). This was a laboratory research with pre and post-test with control group design. Rats were febrile by injecting 20% peptone solution intra-peritoneally and expressed fever if the temperature rise was 1.5 °C from the initial temperature. The test was performed on selected white rats (15) divided into 3 treatment groups: Negative control group, positive control group and Erythrina lithosperma Miq., leaves infusion group in which each group consisted of 5 rats. Temperature measurement was taken every 1 hour for 4 hours (t1, t2, t3 and t4) after treatment. The data of ratâ??s body temperature was analyzed descriptively and statistically by one way Anova test. The results showed that Erythrina lithosperma Miq., leaves infusion had antipyretic effect on white rat (Rattus norvegicus) although not statistically significant.

Biography :

Elisabeth N Barung has completed her Bachelor’s degree in Pharmacy Department from Hasanuddin University and Master’s degree in Faculty of Medicine at Gadjah Mada University, Indonesia. Presently, she is a Lecturer in Pharmacy Department, Health Polytechnic Manado and performing research in the fields of pharmaceuticals and pharmacology, especially in traditional medicine and medicinal dosage formulations.

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