Anjali K Gohel, Tabassum A Khan and Rashmi Mallya
S V K M�??s Dr Bhanuben Nanavati College of Pharmacy, India
Posters-Accepted Abstracts: Nat Prod Chem Res
Herbal therapies are traditionally considered harmless and are increasingly being consumed by people without prescription. The quality assessment of herbal formulations is of paramount importance in order to justify their acceptability in modern system of medicines. Standardization involves set of experiments to be conducted in order to ensure the quality, safety and efficacy of the drug or its formulation. In the present study, four different marketed brands of an Ayurvedic formulation, Balarishta viz. Baidyanath, Dabur, Zandu and Nagarjuna has been standardized with respect to their physicochemical (organoleptic properties, pH, specific gravity, total solid content, total alcohol content, reducing and non-reducing sugar content), phytochemical and microbial parameters (total bacterial count, total fungal count and test for specific pathogens viz. P. aeruginosa, E. coli and S. aureus). A validated HPTLC method for simultaneous identification of three major phytoconstituents present in Balarishta viz. withaferin A, gallic acid and ephedrine has also been developed. This method was used to quantitate the content of withaferin A, gallic acid and ephedrine in all four brands of Balarishta. The stability profile of this formulation under accelerated stability condition, i.e., 40o C, 75% RH for 3 months was accessed. A comparative data of each of the four brands has been generated for all the tests performed.
Email: gohelanjali06@gmail.com
