Osmotic Diuresis is the increased urination due to certain non absorbable substances causing retention of water within the lumen in kidney tubules. It is caused by high blood glucose, urea and medications such as mannitol, excretion occurs with the entry of these substances.
Mechanism of osmotic diuresis: substances that are not easily reabsorbed by the renal tubules are retained in the lumen, resulting an increase in osmotic pressure. With the phenomenon of osmosis, wherein water goes through a semipermeable membrane into a solution of high solute concentration, water then goes to the lumen. This leads to a reduction in water reabsorption, thereby resulting in increased urine output. An increase in the filtration of solutes that could not be reabsorbed by the kidneys, such as urea or glucose, can lead to impaired reabsorption of sodium and water cause osmotic diuresis.
Related Journals of Osmotic Diuresis
Journal of Kidney, Medical & Surgical Urology, Japanese Journal of Nephrology, International Journal of Nephrology and Renovascular Disease, Journal of Renal Care, CardioRenal Medicine.