Khanna S
India
Research Article
From Incompatibility to Accommodation The Journey of Taming Self :
Guide to Perioperative Management of Solid Organ Transplantation
across ABO and Rh Barrier
Author(s): Khanna S, Das J, Kumar S, GhoshP, Jha P, Mehta Y, Ahlawat R and Kher VKhanna S, Das J, Kumar S, GhoshP, Jha P, Mehta Y, Ahlawat R and Kher V
The fate of every organ allografting is ‚rejection’ if nothing is done to halt this natural process. The risks of ‘hyperacute’ ‘accelerated acute’ and ‘acute’ rejection have restricted scientists and clinicians over the years in performing organ transplantationwithin ABO blood group matched pairs only. Subsequent to the development in the field of immunosuppression, ABO incompatible transplants have gained momentum to incorporate a significant population of end stage renal disease patients with incompatible blood group donors into the transplant program. However, optimizing the recipient for transplantation and subsequent accommodation with optimal graft function without tilting to the much easier path of rejection is a challenge. Although most of these steps come under the domain of the nephrologist, it.. View More»
