Department of Paediatric, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Sawangi (Meghe), Maharashtra, India
Case Report
Atypical Haemolytic Uremic Syndrome with Acute Glomerulonephritis in a 15-Year-Old: A Case Report
Author(s): Sneha Kenjale* and Keta Vagha
Atypical haemolytic uremic syndrome is a rare type of thrombotic microangiopathy and one of the common causes of acute kidney injury or acute renal failure in paediatric age group apart from renal hypoperfusion. It consist of 5% classical haemolytic uremic syndrome cases and is differentiated from classical HUS by absence of typical history of preceding diarrhoea due to shiga toxin or verotoxin of enteropathogenic E.coli (O157;H17) and absence of prodromal period. Majority of them have an evidence of intravascular haemolysis manifesting as anaemia, thrombocytopenia and features suggestive of declining renal function. Approximately, 50% cases present with this triad. However, Disease has broad spectrum of clinical features majorly involving renal system and others being central nervous system, ophthalmic lesions, pulmonary system and gastrointestinal system. Most frequent extra renal m.. View More»
